Isolation and Purification of Polyhydroxyalkanoates. Scaling in Pilot Production

The process of isolating and purifying poly-3-hydroxybutyrate under scaling conditions has been studied. Sodium dodecyl sulfate, sodium hypochlorite and Pemos washing powder were studied as solubilizing agents. The highest yield of 95 % and polymer purity of 99.5 % was achieved using a two- stage extraction method and Pemos powder as a solubilizing agent. As a result, it was possible to reduce the costs at the solubilization stage to 31 rubles/kg of poly-3-hydroxybutyrate. Based on the research results, a technology for the isolation and purification of polyhydroxyalkanoates was proposed.