Synthesis of ()-N-acyl norepinephrine and its analogs

Changkuo Zhao, Han Lin, Linming Zuo, Hongzhuo Wei,Xianheng Wang

JOURNAL OF MOLECULAR STRUCTURE（2024）

引用 0|浏览3

暂无评分

摘要

A convenient method to prepare (+/-)-N-acyl norepinephrine derivatives has been developed, one of which (R = CH3) was an important active ingredient isolated from Aspongopus chinensis Dallas. To full acylated norepinephrine 3, different de-protection conditions will afford different products (4 or 5) selectively. The structure was identified by H-1 NMR, C-13 NMR, HRMS and X-ray spectra.

查看译文

关键词

Methoxylation,Acylation,Regio-selectivity,Total synthesis,(+/-)-N-acyl norepinephrine

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要