Remote medical monitoring of outpatient oncological female patients

Due to the immunosuppressive effect of oncological therapies, this patient collective is particularly at risk of infections. In the case of a COVID("coronavirus disease")-19 infection, these patients have a high risk of dying, especially when the disease is progressive. In addition to the COVID-19 infection itself, modifications or postponement of chemotherapy cycles during the pandemic had a high potential risk of endangerment for oncology patients: these lead to disease progression and are associated with an earlier death. We therefore designed a prospective monocentric cohort study to identify morbidity-promoting factors using patient reported outcome monitoring (PROM) via an app and remote monitoring via an ear sensor. The use of these technologies should enable early detection of infections and thus the initiation of a medical intervention and prevent treatment modifications correlating with a poor outcome. Furthermore, participating female patients should be provided with a higher level of safety due to the possibility of early detection of infections through monitoring as part of the study. The study was conducted as a feasibility analysis in cooperation with the Clinic for Cardiology at the Klinikum rechts der Isar of the Technical University of Munich (TUM). Primary endpoints were adherence (after wearing time) and technical robustness. For remote monitoring, the infrastructure of the TUM Telemedicine Center was used with the long-term goal of establishing an expandable remote monitoring infrastructure for the public health system.