An Efficient Synthesis and Characterization of Amine and Amide Derivatives of Ethyl 6-(trifluoromethyl)nicotinate

A new bioactive amine and amide derivatives of trifluoromethyl pyridine was produced with good yields from commercially accessible and inexpensive starting materials and characterized using 1HNMR, 13CNMR, and mass spectrum analysis. We prepared all the intermediates in gram scale, it will be viable for industrial production, because the compounds contain a bioactive core component, trifluoromethylpyridine, they will be useful in developing new insecticides with improved therapeutic action. Due to the presence of trifluoromethyl pyridine functional group in a wide range of pesticides and insecticides, we have prepared the amide and amine derivatives of trifluoromethyl pyridines from the commercially available and inexpensive starting materials. These molecules will be very useful for the development of novel insecticide and pesticides for the improved therapeutic activity.image