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MicroRNA biosensors for detection of glioblastoma

Mehdi Fattahi, Mohadese Maghsudlu,Masoumeh Razipour,Ahmad Movahedpour,Mohsen Ghadami,Mehdi Alizadeh,Seyyed Hossein Khatami,Mortaza Taheri-Anganeh, Ehsan Ghasemi,Hassan Ghasemi,Saleh Aiiashi, Elham Ghadami

CLINICA CHIMICA ACTA（2024）

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Abstract
Glioblastoma (GBM) is the most common type of malignant brain tumor. The discovery of microRNAs and their unique properties have made them suitable tools as biomarkers for cancer diagnosis, prognosis, and evaluation of therapeutic response using different types of nanomaterials as sensitive and specific biosensors. In this review, we discuss microRNA-based electrochemical biosensing systems and the use of nanoparticles in the evolving development of microRNA-based biosensors in glioblastoma.
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Cancer,Biomarker,Diagnosis,microRNA
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