Discovery of Novel TLR7 Agonists As Systemic Agent for Combination with Apd1 for Use in Immuno-oncology.
Yam B. Poudel,Liqi He, Matthew Cox,Qian Zhang,Walter L. Johnson,Qiang Cong,Heng Cheng,Naidu S. Chowdari,Christine Tarby,Andrew F. Donnell, Matthais Broekema,Daniel P. O'Malley,Yong Zhang,Murugaiah A. M. Subbaiah, Boda Vijay Kumar,Lakshumanan Subramani, Bei Wang,Yi-Xin Li,Prasanna Sivaprakasam,David Critton, Dawn Mulligan, Bhupindar Sandhu,Chunshan Xie,Radha Ramakrishnan,Jignesh Nagar,Shailesh Dudhgaonkar,Martins S. Oderinde,Anwar Murtaza,Gary L. Schieven,Arvind Mathur,Ashvinikumar V. Gavai,Gregory Vite,Sanjeev Gangwar ACS Medicinal Chemistry Letters（2024）
Key words
TLR7 agonist,tumor,immuno-oncology,cancer,PD1
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