Internal exposure potential of water-soluble organic molecules in urban PM2.5 evaluated by non-covalent adductome of human serum albumin

Yaling Zeng,Antai Zhang,Xin Yang,Chunbo Xing,Jinghao Zhai,Yixiang Wang,Baohua Cai, Shao Shi,Yujie Zhang,Zhenxing Shen,Tzung-May Fu,Lei Zhu,Huizhong Shen,Jianhuai Ye,Chen Wang

Environment International（2024）

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摘要

•9,484 PM2.5 organic molecules formed human serum albumin adductome, indicating internal exposure potential.•Internalizable PM2.5 fraction varied 11.9–61.3%, averaging 26.2%.•Lignin-like and lipid-like WSOM were primarily responsible for the internal exposure potential.

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关键词

Non-covalent adductome,Internal exposure,Non-target analysis,Surface plasmon resonance

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