The Association Between C24:0/C16:0 Ceramide Ratio and Cardiorespiratory Fitness is Robust to Effect Modifications by Age and Sex.

Jule Zatloukal,Stephanie Zylla,Marcello R P Markus,Ralf Ewert,Sven Gläser,Henry Völzke,Diana Albrecht,Nele Friedrich,Matthias Nauck,Linda R Peterson,Xuntian Jiang,Jean E Schaffer,Stephan B Felix,Marcus Dörr,Martin Bahls,Stefan Gross

Advanced biology（2024）

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Abstract

Ceramides and cardiorespiratory (CR) fitness are both related to cardiovascular diseases. The associations of three blood plasma ceramides (C16:0, C22:0, and C24:0) with CR fitness in the population-based Study of Health in Pomerania (SHIP-START-1; n = 1,102; mean age 50.3 years, 51.5% women) are investigated. In addition, subgroup analysis according to age (More

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