The Impact of Oral Probiotics on Laboratory Parameters in Patients With Alcohol Toxicity: A Single-blinded Intervention Study

INTERNATIONAL JOURNAL OF MEDICAL TOXICOLOGY AND FORENSIC MEDICINE(2024)

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Abstract
Background: Alcohol toxicity is a significant medical emergency with implications for patient management and outcomes. This single -blinded randomized intervention study investigated the effects of oral probiotics on various laboratory parameters in patients with acute alcohol toxicity. Methods: A total of 30 eligible patients were randomly assigned to either the control (placebo) or intervention (oral probiotics) group. Results: While the study did not reveal a significant impact on the length of hospital stay (LOHS), it did demonstrate notable improvements in laboratory variables, including pH, serum glutathione level, serum vitamin B6 level, and O-2 saturation, in the probiotic group. Conclusion: These findings suggest the potential benefits of probiotics in mitigating certain aspects of alcohol toxicity.
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Key words
Oral probiotics,Alcohol toxicity,Laboratory parameters
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