[A Case of Lymph Nodes Metastases of Gastric Neuroendocrine Carcinoma Treated with Nivolumab and Showing Complete Response].

Noriko Wada, Ko Takachi, Yumi Shirosaki, Masataka Fujiwara, Nijie Fukuda,Yusuke Matsuura,Koji Munakata,Daisuke Takiuchi,Naoki Hama,Hirofumi Ota

Gan to kagaku ryoho. Cancer & chemotherapy(2023)

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摘要
A 78-year-old man was diagnosed with lymph node metastasis 2 months after surgery for gastric neuroendocrine carcinoma. He received chemotherapy(CDDP plus CPT-11)and showed partial response(PR)after 3 courses of the regimen. Serum CEA increased 5 months after surgery, thus nab-paclitaxel plus ramucirumab was administered. Although the lymph node kept shrinked after 2 courses of the regimen, the lymph node was detected 12 cm of the size in CT after 5 courses of the regimen. He started to receive nivolumab. The lymph nodes showed PR after 4 courses, and complete response after 6 courses of the regimen for 1 year and 4 months until now.
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