Complete reference genomes of two ceftriaxone-resistant Neisseria gonorrhoeae strains identified in routine surveillance in Bangkok, Thailand, using Nanopore Q20+ chemistry, VolTRAX V2b, and Illumina sequencing

Pongsathorn Sangprasert,Daniel Golparian,Porntip Paopang, Natnaree Girdthep,Ratana Lawung,Deyer Gopinath, Panithee Thammawijaya, Rossaphorn Kittiyaowanarn,Magnus Unemo

MICROBIOLOGY RESOURCE ANNOUNCEMENTS(2024)

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摘要
Ceftriaxone-resistant Neisseria gonorrhoeae strains, mostly associated with Asia, threaten gonorrhea treatment. We report the reference genomes of two ceftriaxone-resistant isolates found in routine surveillance in Bangkok, Thailand. The genomes belonged to the more antimicrobial-susceptible genomic lineage B, illustrating that both ceftriaxone-resistant strains and the mosaic penA-60.001 ceftriaxone-resistance determinant are spreading.
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Neisseria gonorrhoeae,ceftriaxone resistance,Thailand
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