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Validity, feasibility, and effectiveness of a voice-recognition based digital cognitive screener for dementia and mild cognitive impairment in community-dwelling older Chinese adults: A large-scale implementation study

Xuhao Zhao, Haoxuan Wen, Guohai Xu, Ting Pang, Yaping Zhang, Xindi He, Ruofei Hu, Ming Yan, Christopher Chen, Xifeng Wu, Xin Xu

ALZHEIMERS & DEMENTIA(2024)

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Abstract
INTRODUCTION: We investigated the validity, feasibility, and effectiveness of a voice recognition-based digital cognitive screener (DCS), for detecting dementia and mild cognitive impairment (MCI) in a large-scale community of elderly participants. METHODS: Eligible participants completed demographic, cognitive, functional assessments and the DCS. Neuropsychological tests were used to assess domain-specific and global cognition, while the diagnosis of MCI and dementia relied on the Clinical Dementia Rating Scale. RESULTS: Among the 11,186 participants, the DCS showed high completion rates (97.5%) and a short administration time (5.9 min) across gender, age, and education groups. The DCS demonstrated areas under the receiver operating characteristics curve (AUCs) of 0.95 and 0.83 for dementia and MCI detection, respectively, among 328 participants in the validation phase. Furthermore, the DCS resulted in time savings of 16.2% to 36.0% compared to the Mini-Mental State Examination (MMSE) and Montral Cognitive Assessment (MoCA). DISCUSSION: This study suggests that the DCS is an effective and efficient tool for dementia andMCI case-finding in large-scale cognitive screening.
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Key words
community-dwelling older adults,dementia,digital cognitive screening,effectiveness,feasibility,large scale,mild cognitive impairment,validity
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