Plasticity

This chapter discusses the landmark paper ‘Neuronal plasticity: increasing the gain in pain’, published by Woolf and Salter in 2000. Excellent review articles not only give a concise overview of a topic but also provide a framework for future research. In 2000, Clifford Woolf and Michael Salter joined forces to write one of the most highly cited review articles in the field of pain research and thus provided a conceptual framework for the plastic changes that occur in nociceptive neurons in response to chronic pain. With over 2,700 citations, this review is one of those rare articles that is still appreciated by pain researchers across domains.