Gamma-Delta T Cells as Orally Induced Suppressor Cells in Rats:In VitroCharacterization

Gerhild Wildner,Stephan Thurau,Maria Diedrichs-Möhring

Annals of the New York Academy of Sciences（2004）

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摘要

Gamma-delta T cells from orally tolerized rats adoptively transfer suppression of experimental autoimmune uveitis. In vivo and in vitro these regulatory cells specifically recognize retinal autoantigen peptide PDSAg and its mimotope B27PD, but not other mimicry peptides. Proliferation of γ/δ T cells was MHC class II and CD8 dependent.

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关键词

suppressor cells,gamma-delta

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