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Study of the Antitumor Activity in Vitro of Iodo-δ-Lactones of 5Z,9Z-Dienoic Acid

E. Kh. Makarova,I. V. Ishbulatov,A. A. Makarov,L. U. Dzhemileva, U. M. Dzhemilev,V. A. D’yakonov

Doklady Chemistry（2024）

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Abstract
Previously unknown phenyl-substituted iodo-δ-lactone derived from 11‑phenylundeca-5Z,9Z-dienoic acid was synthesized in 94
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Key words
cross-cyclomagnesiation,1,2-dienes,iodo-δ-lactones,Cp2TiCl2,cytotoxic activity,apoptosis,Jurkat,K562,U937,HL60,HEK293
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