Age- and Race-Specific Changes in ESKD Incidence over Four Decades
Chyng-Wen Fwu,Paul W. Eggers,Jenna M. Norton,Debbie S. Gipson,Paul L. Kimmel,Ivonne H. Schulman,Kevin E. Chan,Kara Bennett,Susan R. Mendley
Journal of the American Society of Nephrology : JASN(2024)
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Abstract
Background: Substantial changes in ESKD incidence over four decades among Black and White Americans of different ages have been incompletely explored. Methods: We analyzed United States Renal Data System data from 1980 to 2019 to determine ESKD incidence trends among Black and White adolescent (13-17 years), adult (18-64 years), and older adult (>= 65) populations. We used the National Cancer Institute Joinpoint Regression Program to estimate annual percent change (APC) in ESKD incidence and to define points in time where a statistically significant change in APC slope occurred for each group. Results: ESKD incidence rose after 1980 for all groups, although the trends differed ( P < 0.001). Growth in incidence slowed for most by 1993, and by 2006, the APC in ESKD incidence had declined for all groups, except White adults, for whom rates continued to rise ( P < 0.05). By 2019, ESKD incidence among Black and White adolescents nearly returned to 1980 levels, but no other group achieved that degree of improvement. Nonetheless, the ESKD incidence among Black American patients exceeds that of White patients in every age group. Conclusions: Distinct patterns in ESKD incidence among patients of different age, sex, and racial groups are shown. These findings could reflect changes in dialysis acceptance rates, access to preventive health care, incidence of diabetes mellitus, implementation of evidence-based guidelines for treatment of CKD, or other unrecognized factors. Copyright (c) 2024 by the American Society of Nephrology.
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Key words
children,chronic kidney failure,chronic renal failure,health equity, diversity, and inclusion,kidney failure,minority health and disparities,renal failure,ESKD
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