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Seeing through the fog: a neuroendocrine explanation for post-COVID cognitive deficits

S. Rasika,Ruben Nogueiras,Markus Schwaninger,Vincent Prevot

Nature Reviews Endocrinology（2024）

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Abstract
Gonadotropin-releasing hormone is implicated in cognitive functions, and its loss is a factor in pathological brain ageing. There are similarities between these processes and the neurological and cognitive deficits observed in patients with long COVID. Here, we explore the hypothesis that neuroanatomical and transcriptomic alterations associated with long COVID could stem from this neuroendocrine perturbation.
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