The γδ T cells dual function and crosstalk with intestinal flora in treating colorectal cancer is a promising area of study

Peizhe Lin, Yijing Yan,Ze Zhang,Qiutong Dong,Jia Yi,Qingbo Li,Ao Zhang,Xianbin Kong

International Immunopharmacology（2023）

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摘要

•Summarized the γδ T cells play both pro-carcinogenic and anti-tumor roles in colorectal cancer.•Revealed the γδ T cells' different roles related to different activation pathways.•Discussed the specific mechanism of γδ T cells in pro-carcinogenic and anti-tumor functions.•Revealed the interaction between intestinal flora and γδ T cells.

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关键词

Colorectal cancer,γδ T cell,Intestinal flora,Anti-tumor function,Tumor-promoting function

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