reduced Cytokine Release Syndrome and improved Outcomes with Earlier Immunosuppressive Therapy in Haploidentical Stem Cell Transplant
Transplantation and Cellular Therapy（2024）
Abstract
•Earlier immunosuppression associated with decreased rates of cytokine release syndrome•Modified post-transplant cyclophosphamide regimen associated with reduced risk of graft-versus-host disease•Haplo-CRS associated with decreased graft-versus-host disease-free, relapse-free survival•More research needed to determine best timing of haplo-transplant immunosuppression
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Key words
Haploidentical transplant,cyclophosphamide,cytokine release syndrome
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