-Globin Expression is Regulated by SUV4-20h1

Yadong Wang,G. Rank,Z. Li, Jia Ju,Alexander Nuber,Yupeng Wu,Ming Liu, Ming Nie,Feifei Huang,L. Cerruti, Chunyan Ma,Renxiang Tan,Gunnar Schotta,Stephen M. Jane,Changjiang Zeng, Qingshun Zhao

Haematologica（2016）

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Abstract

Research efforts to establish therapeutic modalities for treating sickle cell disease (SCD) and β-thalassemia have been hindered by our incomplete understanding of the developmental regulation of human β-like globin gene expression. It has been demonstrated that increased embryonic globin (e-

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