Modified medication use in dysphagia: the effect of thickener on drug bioavailability—a systematic review
European Geriatric Medicine(2024)
Abstract
Key summary points Aim To understand further the effect of thickener on medications and their pharmacokinetic and therapeutic profiles, using a literature search. Findings Despite dysphagia and polypharmacy being common in older adults, little is known about the effects of altering liquid viscosity on the pharmacokinetics and therapeutic effect of most medications. Message Further work must be undertaken to support clinicians, pharmacists and patients in understanding the effects of thickener.
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Key words
Dysphagia,Swallowing,Thickener,Modified diets,Thickened-liquids,Bioavailability
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