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Synthesis and Antichlamydial Activity of Oleanolic Acid Aza-Derivatives

O. B. Kazakova, L. V. Rubanik,A. V. Petrova,I. E. Smirnova, A. V. Terekhova,I. P. Baikova

Chemistry of Natural Compounds（2024）

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Abstract
Modification of oleanolic acid synthesized new N -containing derivatives with amino- and azepano-fragments in rings A and C that were highly active against C. trachomatis with a chemotherapeutic index > 8.
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Key words
oleanolic acid,synthesis,aza-derivatives,Chlamydia trachomatis,antichlamydial activity
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