A rare case of MET exon 14 skipping mutation-positive pulmonary sarcomatoid carcinoma with pancreatic metastasis
Respiratory Medicine Case Reports(2023)
摘要
Lung sarcomatoid carcinoma is a rare tumor. We report a rare case of pancreatic metastasis in a 76-year-old man with lung sarcomatoid carcinoma. Right upper lobectomy was performed, and the patient was diagnosed with pulmonary sarcomatoid carcinoma with a MET exon 14 skipping mutation. A biopsy of the pancreatic lesion subsequently revealed pancreatic metastasis. A MET exon 14 skipping mutation was confirmed, and the patient was treated with a MET tyrosine kinase inhibitor and maintained a complete response for 2 years. Lung sarcomatoid carcinoma rarely metastasizes to the pancreas and can be adequately treated with a MET tyrosine kinase inhibitor.
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关键词
sarcomatoid carcinoma,Metastasis,MET exon 14,Protein kinase inhibitor,Genetic mutation
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