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CircBUB1 activates the PI3K/AKT signaling pathway to promote the migration and invasion of glioblastoma cells

Runan Zhang,Dongmei Wu, Ying Wang,Liping Wu,Guowei Gao,Dayong Shan

Neuropeptides（2023）

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Abstract
•CircBUB1 is expressed at a high level in GBM cells.•CircBUB1 knockdown represses the migration and invasion of GBM cells.•CircBUB1 competitively binds with miR-1296-5p to up-regulate TRIM14.
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Key words
Glioblastoma,circBUB1,TRIM14,PTEN,PI3K/AKT signaling pathway
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