Acceptability of gynecologic e-health modalities by Hispanic/Latina women of reproductive age

•This cross-sectional study was designed to determine the perception of Hispanic/Latina women of reproductive age regarding facilitators and barriers for using e-Health modalities, including mobile apps and telemedicine, to monitor gynecologic health.•This is, to our knowledge, the first effort to generate data on gynecological e-Health adoption by Hispanic/Latina women who are disproportionally affected by health disparities.•The study identified gaps, needs, barriers and opportunities to reach equity in access to e-Health for this population through informing health policy. While the study was conducted in Puerto Rican women, its results can be impactful for other Hispanic/Latina women in other world regions, including Latin America, North America and Spain.