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HIGH FUROSEMIDE DOSE IS AN INDEPENDENT RISK FACTOR FOR MORTALITY IN PATIENTS WITH CHRONIC HEART FAILURE

John V Terrovitis,Christos Kapelios,Elisavet Kaldara,George Sainis,Vassilios Sousonis,Nickolaos Michelinakis,Stefania Sventzouri,Zafeiria Margari,Argyrios Ntalianis,John N Nanas

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2012）

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Abstract
Diuretics relieve congestion in HF patients but activate the renin-angiotensin-aldosterone system (RAAS). High furosemide doses have been correlated with higher mortality; it is not clear whether higher diuretic doses represent a marker of disease severity or an independent prognostic factor. We
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Key words
high furosemide dose,chronic heart failure,heart failure,mortality
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