Association between elevated white blood cell counts and thrombotic events in polycythemia vera: Analysis from REVEAL

Aaron T. Gerds,Ruben Mesa,John M. Burke,Michael R. Grunwald,Brady L. Stein,Peg Squier,Jingbo Yu,J.E. Hamer-Maansson,Stephen T. Oh

Blood（2023）

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摘要

•REVEAL is a prospective observational study that enrolled 2510 patients with PV, with a median (range) follow up of 44.7 (2-59) months.•Acute and sustained WBC count elevation was significantly associated with increased thrombotic event risk, even with hematocrit ≤45%.

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