Residual Immunity from Smallpox Vaccination and Possible Protection from Mpox, China.

Yu Huang,Li Guo, Yanan Li,Lili Ren, Jiqin Nie,Fengwen Xu,Tingxuan Huang,Jingchuan Zhong,Zhangling Fan, Yin Zhang, Yu Xie,Qiao Zhang,Shan Mei, Yan Xiao,Xinming Wang,Liuhui Xu,Fei Guo,Jianwei Wang

Emerging Infectious Diseases（2024）

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摘要

Among persons born in China before 1980 and tested for vaccinia virus Tiantan strain (VVT), 28.7% (137/478) had neutralizing antibodies, 71.4% (25/35) had memory B-cell responses, and 65.7% (23/35) had memory T-cell responses to VVT. Because of cross-immunity between the viruses, these findings can help guide mpox vaccination strategies in China.

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关键词

vaccinia virus,smallpox,mpox,monkeypox,viruses,neutralizing antibodies

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