Development of a biofidelic computational model of human pelvis for predicting biomechanical responses and pelvic fractures

Background and objective: The pelvis, a crucial structure for human locomotion, is susceptible to injuries resulting in significant morbidity and disability. This study aims to introduce and validate a biofidelic computational pelvis model, enhancing our understanding of pelvis injury mechanisms under lateral loading conditions. Methods: The Finite Element (FE) pelvic model, representing a mid -sized male, was developed with variable cortical thickness in pelvis bones. Material properties were determined through a synthesis of existing constitutive models, parametric studies, and multiple validations. Comprehensive validation included various tests, such as load -displacement assessments of sacroiliac joints, quasi -static and dynamic lateral compression on the acetabulum, dynamic side impacts on the acetabulum and iliac wing using defleshed pelvis, and lateral impacts by a rigid plate on the full body's pelvis region. Results: Simulation results demonstrated a reasonable correlation between the pelvis model's overall response and cadaveric testing data. Predicted fracture patterns of the isolated pelvis exhibited fair agreement with experimental results. Conclusions: This study introduces a credible computational model, providing valuable biomechanical insights into the pelvis' response under diverse lateral loading conditions and fracture patterns. The work establishes a robust framework for developing and enhancing the biofidelity of pelvis FE models through a multi -level validation approach, stimulating further research in modeling, validation, and experimental studies related to pelvic injuries. The findings are expected to offer critical perspectives for predicting, preventing, and mitigating pelvic injuries from vehicular accidents, contributing to advancements in clinical research on medical treatments for pelvic fractures.