Association between blood hormones and fecundity in rabbit does

The aim of the present study was to examine the association between blood hormone level and fecundity in rabbit does. The ovulation of nulliparous New Zealand White rabbits was induced by administration of PMSG and LH-RH analogue. Next day, the does were inseminated, blood was collected and the plasma levels of IGF-I, leptin, progesterone and estradiol were measured by radioimmunoassay. After the birth of pups, the retrospective comparison of level of hormones in the blood of fertile and non-fertile animals was performed. Fertile does had significantly higher blood level of IGF-I and lower concentration of leptin than the infertile ones. No significant differences in blood progesterone and estradiol level was found between fertile and non-fertile females. These observations suggest that blood IGF-I and leptin level could be useful for diagnostics and prediction of rabbit does' fecundity.