Interventions targeting LGBTQIA+ populations to advance health equity.

•LGBTQIA+ populations are relevant components of our society and are increasing numerically, but they unfortunately face health and health care inequities.•Each gender identity and sexual orientation has its own cluster of risk factors and healthcare needs.•Health workforce should be a point of strength in the fight against any type of discrimination.•Modernizing and expanding gender, sex and sexual orientation information practices may inform the development and equitable implementation of prevention and treatment guidelines for the growing LGBTQIA+ population: successfully collecting, recording, storing and using accurate GSSO data is key to ensuring that any health inequality for all SGM is overcome.