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Rational in Silico Design Identifies Two Mutations That Restore UT28K SARS-CoV-2 Monoclonal Antibody Activity Against Omicron BA.1.

Tatsuhiko Ozawa, Yoshiki Ikeda, Liuan Chen,Rigel Suzuki,Atsushi Hoshino,Akira Noguchi,Shunsuke Kita,Yuki Anraku,Emiko Igarashi,Yumiko Saga,Noriko Inasaki,Shunta Taminishi,Jiei Sasaki,Yuhei Kirita,Hideo Fukuhara,Katsumi Maenaka,Takao Hashiguchi,Takasuke Fukuhara,Kenichi Hirabayashi,Hideki Tani,Hiroyuki Kishi,Hideki Niimi

STRUCTURE（2024）

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Key words
in silico designed,neutralizing antibodies,SARS-CoV-2
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