Developing ChatGPT for Biology and Medicine: A Complete Review of Biomedical Question Answering
Biophysics Reports(2024)
摘要
ChatGPT explores a strategic blueprint of question answering (QA) in
delivering medical diagnosis, treatment recommendations, and other healthcare
support. This is achieved through the increasing incorporation of medical
domain data via natural language processing (NLP) and multimodal paradigms. By
transitioning the distribution of text, images, videos, and other modalities
from the general domain to the medical domain, these techniques have expedited
the progress of medical domain question answering (MDQA). They bridge the gap
between human natural language and sophisticated medical domain knowledge or
expert manual annotations, handling large-scale, diverse, unbalanced, or even
unlabeled data analysis scenarios in medical contexts. Central to our focus is
the utilizing of language models and multimodal paradigms for medical question
answering, aiming to guide the research community in selecting appropriate
mechanisms for their specific medical research requirements. Specialized tasks
such as unimodal-related question answering, reading comprehension, reasoning,
diagnosis, relation extraction, probability modeling, and others, as well as
multimodal-related tasks like vision question answering, image caption,
cross-modal retrieval, report summarization, and generation, are discussed in
detail. Each section delves into the intricate specifics of the respective
method under consideration. This paper highlights the structures and
advancements of medical domain explorations against general domain methods,
emphasizing their applications across different tasks and datasets. It also
outlines current challenges and opportunities for future medical domain
research, paving the way for continued innovation and application in this
rapidly evolving field.
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