Effects of Carbomer Eye Gels on the Ocular Surface in Dry Eye Patients

Purpose: We investigated the clinical effects of Siccafluid carbomer eye gel on the symptoms, tear film, and ocular surface in dry eye patients. Methods: Fifty-five patients with dry eye syndrome were also treated with carbomer eye gel for 6 months. The Dry Eye Questionnaire (DEQ-5), tear film breakup time (TBUT), Schirmer's test, and ocular surface staining score were assessed during follow-up. Patients were classified into Sjogren's syndrome and non-Sjogren's syndrome groups and the effects of the carbomer eye drops in each group were analyzed. Results: Overall, the dry eye patients showed significant improvement in the total DEQ-5 score, frequency and intensity of dryness, and TBUT 6 months after treatment. In the non-Sjogren's group, the total DEQ-5 score, intensity of dryness, and TBUT improved, while in the Sjogren's group, the total DEQ-5 score, frequency and intensity of dryness, and TBUT improved. In both groups, patients with a shorter TBUT showed a significant improvement in the total DEQ-5 score. Conclusions: After 6 months of carbomer eye gel use in patients with dry eye syndrome, the symptoms of ocular dryness and tear film breakup time improved. In patients with dry eye syndrome who have a short TBUT, this can be an effective treatment for alleviating dry eye symptoms. J Korean Ophthalmol Soc 2024;65(1):9-15