-Acyloxylation of Ketones/Cyclic Ethers Mediated by Hypervalent Iodine(III) Reagents as Oxidants and Nucleophilic Sources

This study describes a catalyst-free alpha-acyloxylation of ketones and a KBr-mediated alpha-acyloxylation of cyclic ethers. These conversions are effectively mediated by hypervalent iodine-(III) reagents serving dual roles as the oxidant and nucleophilic source. Consequently, esters are produced directly in moderate to excellent yields. The proposed method features good functional group compatibility, a broad substrate scope, and high synthetic efficiency and is remarkably environmentally friendly.