Predictive clinical and dosimetric parameters for risk of relapse in early-stage non-small cell lung cancer treated by SBRT: A large single institution experience

Clinical and Translational Radiation Oncology(2024)

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摘要
•Impact of dosimetric parameters on efficacy of SBRT in ES-NSCLC, using HyTEC reporting standards.•A large cohort from a single institution to ensure consistent treatment methods.•This study could potentially resolve many errors that can occur in pooled studies.•A higher percent of GTV receiving ≥110 % of the prescribed dose and a higher GTV Dmax (BED10) seem to allow a better LC.•This is the first study to report the benefit of the percentage of GTV receiving ≥110 % of the prescribed dose on LC.
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关键词
Early-stage non-small cell lung cancer,Stereotactic body radiation therapy,Dosimetric analysis,Local control,Relapse
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