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Introducing the Dynamic Well-Stirred Model for Predicting Hepatic Clearance and Extraction Ratio

Zhengyin Yan,Li Ma,Pasquale Carione,Julie Huang,Nicky Hwang,Jane R. Kenny,Cornelis E. C. A. Hop

Journal of Pharmaceutical Sciences（2024）

Cited 4|Views12
Key words
Clearance prediction,Dynamic free fraction,In vitro in vivo extrapolation,Well-stirred model,Dynamic well-stirred model
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