Identification of coronavirus disease marker compounds in sweat with comprehensive two dimensional gas chromatography using multiloop splitter-based non-cryogenic artificial trapping modulation system

Nuttanee Tungkijanansin,Ryland T. Giebelhaus, Sheri A. Schmidt,Thumnoon Nhujak,Kaywalee Chatdarong,Pattama Torvorapanit,James J. Harynuk,Chadin Kulsing

Journal of Chromatography Open（2024）

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摘要

•GC × GC method using artificial modulation system was developed.•This was applied to analyze COVID-19 related sweat samples.•Data analysis approaches revealed three potential markers.•This was applied to perform COVID-19 screening with up to 98% accuracy.

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关键词

Artificial modulation,COVID-19 analysis,Multidimensional GC,Skin secretion,Volatile markers

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