Treatment and Outcomes of 4,973 Unicameral Bone Cysts: A Systematic Review and Meta-Analysis

Unicameral bone cysts (UBCs) can increase the risk of pathologic fractures of both long and short bones. Although multiple treatments exist, data are conflicting regarding optimal management.We sought to analyze treatment strategies for UBCs and their rates of successful treatment.Success rates were analyzed according to treatment modality, with emphasis on filling techniques and/or decompression associated with curettage, and injection compounds.Curettage with bone substitute and cyst decompression was identified as a highly successful technique for UBC treatment.Decompressing the cyst wall after injection, regardless of the specific compound used, had a greater potential to enhance healing rates.The management decision should be individually guided within the patient's context.