Older Adults With Inflammatory Bowel Disease Are at Higher Risk of Developing Antibodies to Infliximab

Adam S. Faye,Kate E. Lee,David Hudesman,Thierry Dervieux

INFLAMMATORY BOWEL DISEASES（2024）

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摘要

Although older age is thought to confer immunosenescence, we found that older adults with inflammatory bowel disease are independently at higher risk to develop antibodies to infliximab. Additionally, older adults are less likely to receive escalated doses of infliximab.

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inflammatory bowel disease,antibodies,biologics,infliximab,anti-TNF,older age,immunosenescence,geriatrics

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