Periplogenin inhibits pathologic synovial proliferation and infiltration in rheumatsuoid arthritis by regulating the JAK2/3-STAT3 pathway

Xiaoqin Zhong,Wei Feng, Lianjie Liu,Qingping Liu, Qiang Xu,Minying Liu,Xiaobao Liu,Shudi Xu,Minzhen Deng,Changsong Lin

International Immunopharmacology（2024）

引用 0|浏览7

暂无评分

摘要

•The migration and infiltration of fibroblast-like synoviocytes in rheumatoid arthritis have been observed both in vivo and in vitro studies.•The JAK2/3-STAT3 pathway was activated in both in vivo and in vitro studies.•Periplogenin has been found to inhibit the activation of the JAK2/3-STAT3 pathway in both in vivo and in vitro studies, which can help alleviate the symptoms of rheumatoid arthritis.

查看译文

关键词

Periplogenin,Rheumatoid arthritis,Synovial fibroblasts,JAK2/3-STAT3

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要