The High Sensitivity of the Multi-Cancer Detection Test ONCOVERYX-F Offers a Promising Platform for Ovarian Cancer Screening

Rajnish Nagarkar, Mamillapalli Gopichand, Suparna Kanti Pal,Ankur Gupta,Najmuddin Mohd Saquib,Ganga Sagar,Kanury V. S. Rao,Zaved Siddiqui, Imliwati Longkumer

INTERNATIONAL JOURNAL OF WOMENS HEALTH(2024)

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Abstract
We evaluated the potential relevance of our multi-cancer detection test, OncoVeryx-F, for ovarian cancer screening. For this, we compared its accuracy with that of CA125-based screening. We demonstrate here that, in contrast to CA125-based detection, OncoVeryx-F detected ovarian cancer with very high sensitivity and specificity. Importantly here, Stage I cancers too could be detected with an accuracy of >98%. Furthermore, again unlike CA 125, the detection accuracy of OncoVeryx-F remained comparable in both Caucasian and South Asian/Indian women. Thus, the robustness and accuracy of OncoVeryx-F, particularly for early-stage detection, underscores its potential utility for ovarian cancer screening.
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Key words
CA 125,Oncoveryx-F,OvC,NoC,LC-MS/MS
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