Small-molecule Inhibition of Kinesin KIF18A Reveals a Mitotic Vulnerability Enriched in Chromosomally Unstable Cancers
Marc Payton,Brian Belmontes,Kelly Hanestad,Jodi Moriguchi,Kui Chen,John D. McCarter,Grace Chung,Maria Stefania Ninniri,Jan Sun,Raffi Manoukian,Stuart Chambers, Seok-Man Ho,Robert J. M. Kurzeja,Katheryne Z. Edson,Upendra P. Dahal,Tian Wu,Sharon Wannberg,Pedro J. Beltran,Jude Canon,Andrew S. Boghossian,Matthew G. Rees,Melissa M. Ronan,Jennifer A. Roth,Sheroy Minocherhomji,Matthew P. Bourbeau,Jennifer R. Allen,Angela Coxon,Nuria A. Tamayo,Paul E. Hughes Nature Cancer（2024）
Key words
Chromosomal Instability,Tumor Suppression
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