Comparison of RLP and PCNL for large pelvis calculi with CKD

Objectives: To compare the effect and safety of retroperitoneal laparoscopic pyelolithotomy (RLP) and percutaneous nephrolithotomy (PCNL) for large pelvis calculi with chronic kidney disease (CKD).Material and methods: Between June 2017 and July 2021, 62 patients with CKD and large renal pelvis calculi (>4 cm(2)) were treated with RLP. Another 62 patients receiving PCNL served as controls. The perioperative parameters were compared. All patients were followed up for at least 6 months with the stone-free rate and the recovery of renal function evaluated.Results: Significantly longer operation time (101.47 +/- 9.25 vs 62.55 +/- 7.54 min), less drop in hemoglobin level (0.90 +/- 0.38 vs 2.13 +/- 0.80 g/dl), staged operations (0% vs 12.9%), postoperative fever (3.23% vs 16.13%) and delayed bowel movement (3.23% vs 14.52), and shorter hospitalization time (3.90 +/- 1.66 vs 4.72 +/- 1.80 days) were observed in the RLP group (p < 0.05). The stone-free rates were 100% in the RLP group and 88.7% in the PCNL group at the 3-months follow-up (p < 0.05). The serum creatinine level was significantly lower in the RLP group at 24 h (2.81 +/- 1.18 vs 3.00 +/- 1.15 mg/dl) and 1 week (2.08 +/- 1.13 vs 2.34 +/- 1.01 mg/dl) postoperatively (p < 0.05).Conclusions: Although associated with a longer operation time, RLP is a safer and more efficient surgical option for CKD patients with large pelvic stones than PCNL.