Chrome Extension
WeChat Mini Program
Use on ChatGLM
VIPCreated with Sketch.

欧李果浆对失眠小鼠的改善作用及机制

FU Rao, LIANG Zhe, WEN Xin,NI Yuanying

Shipin Kexue（2023）

Cited 0|Views7
No score
Abstract
本研究对'农大4号''农大7号'和'燕山2号'欧李果浆进行体外模拟消化实验,选取γ-氨基丁酸(γ-aminobutyric acid,GABA)含量最高的'农大4号'欧李果浆作为受试物,通过急性毒性试验、高架十字迷宫实验、戊巴比妥钠诱导下小鼠直接睡眠实验、睡眠时间延长实验以及巴比妥钠诱导下小鼠的睡眠潜伏期实验,探究欧李果浆对小鼠睡眠行为的改善作用.结果表明,灌胃800 mg/kg mb欧李果浆能够显著延长失眠小鼠的睡眠时长(P＜0.05),提高小鼠入睡率,缩短睡眠潜伏期,且其改善作用可能与下调血清促炎因子水平和调节下丘脑-垂体-肾上腺轴功能有关.
More
Translated text
Key words
cerasus humilis (bge.) sok,γ-aminobutyric acid,sleep improvement,relieving anxiety,neurotransmitter
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined