Central Regulatory Circuit of the Drosophila Mechanoreceptor Morphogenesis System: Effects of Mutations

D. P. Furman,T. A. Bukharina,V. P. Golubyatnikov

Journal of Applied and Industrial Mathematics（2023）

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摘要

We describe a mathematical model of the functioning of the central regulatory circuit of gene networks for the morphogenesis of Drosophila mechanoreceptors taking into account mutations of the genes included in it. Computational experiments have been carried out showing the existence of a hierarchy of effects of CRC gene mutations on the production of ASC proteins.

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关键词

central regulatory circuit,gene network,mathematical model,parameter identification,computer modeling,Drosophila,achaete-scute complex,mutation

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