Engineered nanopores for exopeptidase protein sequencing

Andrea Bonini, Adina Sauciuc,Giovanni Maglia

Nature Methods(2024)

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摘要
Two studies show that nanopores can identify the 20 proteinogenic amino acids and some of their post-translational modifications. Coupled with an exopeptidase, a bottom-up approach to protein sequencing using nanopores is on the horizon.
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