Efficacy and Safety of Programmed Death-1 (PD-1)/Programmed Death-Ligand 1 (PD-L1) Checkpoint Inhibitors in Patients With Metastatic Castration-resistant Prostate Cancer: A Systematic Review and Meta-analysis

Clinical Oncology(2024)

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Abstract
•Efficacy and safety of PD-1/PD-L1 inhibitors in mCRPC patients was evaluated.•Thirteen studies involving 2533 participants were included in the meta-analysis.•Anti-PD-1/PD-L1 treatment may significantly increase the PFS benefits.
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Key words
Checkpoint inhibitors,meta-analysis,programmed cell death protein 1,programmed death ligand 1,prostate cancer
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