Fully umbilical cord-derived adhesive materials enable to recruit and segregate immune cells for the reversal of acute liver failure
Engineered Regeneration(2024)
摘要
•The fully human tissue-derived adhesive materials enable significant suppression of inflammatory cytokine storms, which breaks the limitations of existing strategies for organ repair based on the molecular level.•The UC-derived adhesive materials achieve highly efficient treatment of ALF in rats with 90% hepatectomy.•The human UC-derived adhesive materials have excellent practicability in clinical organ transplantation-related treatment.
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关键词
Interfacial adhesive materials,Extracellular matrix nanofibers,Hydrogel,Mesenchymal stem cells,Acute liver failure
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