Phytosynthesis of gold-198 nanoparticles for a potential therapeutic radio-photothermal agent
APPLIED RADIATION AND ISOTOPES(2024)
Abstract
We produced spherical gold-198 nanoparticles with an average size of 41 nm, good stability, and high radio-chemical purity for a promising single agent of radio-photothermal therapy using Curcuma longa rhizome extract as a reducing and capping agent. The combination of in vitro treatment using gold-198 nanoparticles and irra-diation of 980 nm wavelength lasers with a power output of 2 W/cm2 induced hyperthermia temperature and exhibited enhancement of the percentage dead on MDA-MB-123 cancer cells compared to gold-198 nanoparticles alone.
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Key words
Gold-198 nanoparticles,Phytosynthesis,Characterization,Cancer cells,Radio-photothermal therapy
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